Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI
From Abstract Results:
“State and local health departments assigned EVALI case status as confirmed for 25 patients and as probable for 26 patients. Vitamin E acetate was identified in BAL fluid obtained from 48 of 51 case patients (94%) in 16 states but not in such fluid obtained from the healthy comparator group. No other priority toxicants were found in BAL fluid from the case patients or the comparator group, except for coconut oil and limonene, which were found in 1 patient each. Among the case patients for whom laboratory or epidemiologic data were available, 47 of 50 (94%) had detectable tetrahydrocannabinol (THC) or its metabolites in BAL fluid or had reported vaping THC products in the 90 days before the onset of illness. Nicotine or its metabolites were detected in 30 of 47 of the case patients (64%).”
None to date.
New England Journal of Medicine
Benjamin C. Blount, Ph.D., Mateusz P. Karwowski, M.D., M.P.H., Peter G. Shields, M.D., Maria Morel-Espinosa, Ph.D., Liza Valentin-Blasini, Ph.D., Michael Gardner, M.S., Martha Braselton, B.S., Christina R. Brosius, M.P.H., Kevin T. Caron, B.S., David Chambers, Ph.D., Joseph Corstvet, B.S., Elizabeth Cowan, Ph.D., et al., for the Lung Injury Response Laboratory Working Group*
Blount BC, Karwowski MP, Shields PG, et al. Vitamin E acetate in bronchoalveolar-lavage fluid associated with EVALI. N Engl J Med 2020;382:697-705.